R448A 25 lb Refrigerant – New Factory-Sealed Cylinder

Specification	R448A
Refrigerant	R448A
Refrigerant Type	HFC/HFO Zeotropic Blend
Components	R32 / R125 / R134a / R1234yf / R1234ze(E)
Composition	26% / 26% / 21% / 20% / 7%
ASHRAE Safety Classification	A1
Ozone Depletion Potential	0
Global Warming Potential	1,386
Cylinder Size	25 lb
Condition	New / Factory Sealed
Primary Application	Commercial / Medium- & Low-Temperature Refrigeration
Charging Method	Liquid Phase

R448A for Commercial Refrigeration

For example, refrigeration professionals use R448A in compatible medium- and low-temperature commercial refrigeration equipment.

R448A has been widely used in supermarket refrigeration, display cases, freezer systems, remote condensing equipment, and other commercial refrigeration applications.

In addition, its A1 safety classification means R448A is classified as lower toxicity and nonflammable under ASHRAE 34.

However, equipment compatibility and current federal requirements should always be verified before installation or retrofit.

R448A as an R404A and R507 Alternative

R448A is commonly used as a lower-GWP alternative to R404A and R507 in compatible commercial refrigeration systems.

Honeywell specifically developed R448A for low- and medium-temperature commercial refrigeration and provides retrofit guidance for R404A systems.

However:

R448A should not be marketed as a universal direct drop-in replacement for every R404A or R507 system.

Before performing a retrofit, a qualified refrigeration professional should evaluate:

• Compressor compatibility
• Lubricant requirements
• Expansion devices
• Refrigerant charge
• System controls
• Operating pressures
• Temperature glide
• Cooling capacity
• Manufacturer recommendations
• Current EPA requirements

Therefore, technicians should follow an approved retrofit procedure for the specific equipment.

R448A and R22 Retrofit Applications

R448A has also been used in certain medium- and low-temperature commercial refrigeration systems originally operating with R22.

However, an R22-to-R448A conversion may require additional system changes.

For example, traditional R22 systems may use mineral oil or alkylbenzene lubricants, while R448A retrofit applications generally require a compatible synthetic lubricant such as POE to provide adequate oil return.

Therefore:

R448A is not a universal direct drop-in replacement for R22.

A qualified HVAC/R professional should evaluate the complete system before conversion.

R448A Charging and Service Considerations

Because R448A is a zeotropic refrigerant blend, technicians should charge it according to the refrigerant and equipment manufacturer’s procedures.

R448A should generally be removed from the cylinder in the liquid phase to maintain the intended refrigerant composition.

Honeywell specifically warns that vapor charging may alter the blend composition and recommends liquid charging during service.

Always follow the cylinder label, SDS, equipment specifications, and established refrigeration service procedures.

Current U.S. Application Considerations

This section is important for R448A because its GWP is 1,386, and current U.S. HFC restrictions vary significantly by refrigeration equipment category.

For example, EPA’s current rules include:

• Remote condensing units: an interim GWP limit of 1,400 applies beginning July 27, 2026.
• Supermarket systems: an interim GWP limit of 1,400 begins January 1, 2027.
• Cold-storage warehouses: a 700 GWP limit took effect July 27, 2026.
• New stand-alone retail-food refrigeration equipment: considerably lower GWP limits already apply.

Because R448A has a GWP of 1,386, its suitability for new equipment depends heavily on the specific equipment category and compliance date.

Factory-Sealed 25 lb Cylinder

We supply each R448A cylinder in new, factory-sealed condition for professional refrigeration applications.

Moreover, factory-sealed packaging helps protect product integrity during storage, handling, and transportation.

For commercial buyers requiring multiple cylinders or recurring supply, contact our team for current inventory, quantity pricing, product documentation, and shipping options.

Why Buy R448A from Imperial Refrigerants?

Imperial Refrigerants supplies refrigerants for refrigeration contractors, HVAC/R service companies, distributors, supermarkets, facility operators, and other commercial buyers.

• New factory-sealed cylinders
• Reliable U.S. refrigerant supply
• Commercial quantity purchasing
• Wholesale pricing options
• Fast order processing
• Responsive customer support
• Product documentation available upon request
• U.S. delivery options

Wholesale R448A Refrigerant Supply

Need multiple 25 lb cylinders of R448A?

We support commercial and wholesale R448A refrigerant orders for refrigeration contractors, service companies, distributors, and other qualified commercial buyers.

In addition, our team can assist with current inventory, volume pricing, product documentation, and available shipping options.

U.S. Refrigerant Purchase Requirements

R448A sold in cylinders for stationary refrigeration applications is subject to EPA refrigerant sales restrictions.

EPA generally restricts purchases of refrigerants for stationary refrigeration and air-conditioning systems to appropriately Section 608-certified technicians or qualifying purchasers buying on behalf of organizations employing certified technicians.

Important Use Information

Qualified refrigeration and HVAC/R professionals should handle, recover, charge, and use R448A in accordance with applicable regulations, equipment manufacturer requirements, and established service procedures.

Always confirm that R448A is approved and currently permitted for the specific equipment, retrofit, and end use before servicing or converting a system.

For current U.S. application requirements, refer to the U.S. EPA Refrigeration and Air Conditioning Substitutes guidance.

Order R448A 25 lb Refrigerant

Looking for a reliable source of R448A in 25 lb cylinders?

Order online or contact Imperial Refrigerants for current inventory, product specifications, commercial quantities, and wholesale pricing.

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