R449A 25 lb Refrigerant – New Factory-Sealed Cylinder
R449A is a lower-GWP HFC/HFO refrigerant blend developed for compatible medium- and low-temperature commercial and industrial refrigeration applications. This 25 lb R449A refrigerant cylinder is supplied new and factory sealed for professional servicing, maintenance, retrofit, and other permitted refrigeration applications.
In addition, Imperial Refrigerants provides reliable U.S. refrigerant supply with responsive customer support and purchasing options for individual cylinders, commercial quantities, and wholesale buyers.
Key Features of R449A Refrigerant
- 25 lb factory-sealed cylinder
- Refrigerant designation: R-449A
- HFC/HFO refrigerant blend
- Components: R32 / R125 / R134a / R1234yf
- Composition: 24.3% / 24.7% / 25.7% / 25.3%
- ASHRAE safety classification: A1
- Ozone depletion potential: 0
- EPA Technology Transitions GWP: 1,396
- Designed for compatible medium- and low-temperature refrigeration
- Suitable for certain approved retrofit applications
- New, factory-sealed packaging
- Commercial and wholesale purchasing options available
EPA confirms R449A’s blend composition, while its current Technology Transitions reference table lists a GWP of 1,396.
R449A Refrigerant Applications
Refrigeration professionals use R449A in compatible commercial and industrial refrigeration systems where equipment specifications, retrofit procedures, and current regulations permit its use.
Typical applications may include:
- Supermarket refrigeration systems
- Commercial display cases
- Walk-in coolers and freezers
- Medium-temperature refrigeration
- Low-temperature refrigeration
- Remote condensing units
- Cold-storage applications where currently permitted
- Industrial process refrigeration
- Compatible R404A/R507 retrofit applications
- Certain compatible R22 refrigeration retrofits
- Certain R407A/R407F refrigeration retrofit applications
Before selecting or charging R449A, always verify the equipment manufacturer’s specifications, retrofit guidance, and applicable U.S. requirements.
For more options, explore our full range of refrigerants for additional commercial refrigeration and HVAC/R applications.
EPA currently lists R449A as acceptable under SNAP in supermarket systems, remote condensing units, cold-storage warehouses, industrial process refrigeration, and several other refrigeration end uses, although separate HFC Technology Transitions limits may still apply to new systems.
R449A Refrigerant Properties
| Specification | R449A |
|---|---|
| Refrigerant | R449A |
| Refrigerant Type | HFC/HFO Blend |
| Components | R32 / R125 / R134a / R1234yf |
| Composition | 24.3% / 24.7% / 25.7% / 25.3% |
| ASHRAE Safety Classification | A1 |
| Ozone Depletion Potential | 0 |
| Global Warming Potential | 1,396 |
| Cylinder Size | 25 lb |
| Condition | New / Factory Sealed |
| Primary Application | Commercial / Medium- & Low-Temperature Refrigeration |
| Charging Method | Liquid Phase |
R449A for Commercial Refrigeration
For example, refrigeration professionals use R449A in compatible medium- and low-temperature commercial refrigeration equipment.
Typical applications include supermarket systems, display cases, walk-in coolers, freezer systems, remote condensing units, and industrial refrigeration equipment.
In addition, R449A carries an A1 safety classification, meaning it is classified as lower toxicity and nonflammable under ASHRAE Standard 34.
However, technicians should always verify equipment compatibility and current federal or state requirements before use.
R449A as an R404A and R507 Alternative
R449A is widely used as a lower-GWP alternative to R404A and R507 in compatible commercial refrigeration systems.
Chemours currently lists R449A as a retrofit option for systems designed around R404A/R507 and notes that retrofit work may require TXV adjustments and other system-specific changes.
However:
R449A is not a universal direct drop-in replacement for every R404A or R507 system.
Before performing a retrofit, a qualified refrigeration professional should evaluate:
- Compressor compatibility
- POE lubricant requirements
- Expansion valves and TXV settings
- Refrigerant charge
- System controls
- Operating pressures
- Discharge temperature
- Cooling capacity
- Manufacturer recommendations
- Current EPA requirements
Therefore, technicians should follow an approved retrofit procedure for the specific refrigeration system.
R449A and R22 Retrofit Applications
R449A may also be used in certain compatible medium- and low-temperature refrigeration systems originally designed for R22.
Chemours specifically provides R449A retrofit guidance for R22 refrigeration systems. Such conversions generally require evaluation of lubricant compatibility and may require changing to POE oil as well as replacing critical elastomeric seals.
Therefore:
R449A is not a universal direct drop-in replacement for R22.
A qualified HVAC/R professional should evaluate the entire refrigeration system before conversion.
R449A Charging and Service Considerations
Because R449A is a zeotropic refrigerant blend, technicians should follow the refrigerant and equipment manufacturer’s charging procedures.
Technicians should generally remove R449A from the cylinder in the liquid phase to help maintain the intended blend composition.
In addition, R449A can have different discharge temperatures, mass flow, and expansion-valve requirements compared with the refrigerant it replaces. Therefore, proper commissioning and system adjustment are important after a retrofit.
Always follow the cylinder label, SDS, manufacturer retrofit guidance, and established refrigeration service practices.
Current U.S. Application Considerations
R449A has a GWP of 1,396 under EPA’s Technology Transitions methodology. This is important because U.S. HFC limits now vary substantially by equipment category.
As of 2026:
- New remote condensing units are subject to an interim 1,400 GWP limit beginning July 27, 2026.
- New supermarket systems will have an interim 1,400 GWP limit beginning January 1, 2027.
- New cold-storage warehouse systems became subject to a 700 GWP interim limit on July 27, 2026.
- Retail-food stand-alone equipment is already subject to much lower GWP limits.
Because R449A is 1,396 GWP, it falls just below the current 1,400 interim limit for certain remote condensing and supermarket systems, but it does not satisfy lower limits such as the 700 GWP requirement for new cold-storage warehouses.
Factory-Sealed 25 lb Cylinder
We supply each R449A cylinder in new, factory-sealed condition for professional refrigeration applications.
Moreover, factory-sealed packaging helps protect product integrity during storage, handling, and transportation.
For commercial buyers requiring multiple cylinders or recurring supply, contact our team for current inventory, quantity pricing, product documentation, and shipping options.
Why Buy R449A from Imperial Refrigerants?
Imperial Refrigerants supplies refrigerants for refrigeration contractors, HVAC/R service companies, distributors, supermarkets, facility operators, and other commercial buyers.
- New factory-sealed cylinders
- Reliable U.S. refrigerant supply
- Commercial quantity purchasing
- Wholesale pricing options
- Fast order processing
- Responsive customer support
- Product documentation available upon request
- U.S. delivery options
Wholesale R449A Refrigerant Supply
Need multiple 25 lb cylinders of R449A?
We support commercial and wholesale R449A refrigerant orders for refrigeration contractors, service companies, distributors, and other qualified commercial buyers.
In addition, our team can assist with current inventory, volume pricing, product documentation, and available shipping options.
U.S. Refrigerant Purchase Requirements
R449A sold in cylinders for stationary refrigeration use is subject to EPA refrigerant sales restrictions.
EPA states that refrigerants intended for stationary refrigeration and air-conditioning equipment generally may only be purchased by appropriately Section 608-certified technicians or qualifying purchasers authorized under the regulation. Sellers are responsible for verifying purchaser eligibility and maintaining required records.
Important Use Information
Qualified refrigeration and HVAC/R professionals should handle, recover, charge, and use R449A in accordance with applicable regulations, manufacturer requirements, retrofit guidelines, and established refrigeration service procedures.
Always confirm that R449A is approved and currently permitted for the specific equipment, retrofit, and end use before servicing or converting a system.
For current U.S. application requirements, refer to the U.S. EPA Refrigeration and Air Conditioning Substitutes guidance.
Order R449A 25 lb Refrigerant
Looking for a reliable source of R449A in 25 lb cylinders?
Order online or contact Imperial Refrigerants for current inventory, product specifications, commercial quantities, and wholesale pricing.
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